OA is caused by wear and tear. A lifetime of bearing weight and moving can simply wear down the cartilage in joints that allow for a full, pain-free range of motion. OA is especially prevalent among people who are on their feet all day in very physical jobs, such as athletes, firefighters, construction workers, warehouse and dock workers and contractors.
OA can also be caused by severe accidents where an injury damages a joint. If a young person is diagnosed with OA, the culprit is usually some type of traumatic, high-impact injury.
Rheumatoid arthritis (RA), an autoimmune disorder, can affect anyone of any age. The body’s immune system essentially misidentifies the synovium as a threat and attacks it. The synovium can be thought of as a soft-tissue bubble that surrounds joints and manufactures a special liquid that helps lubricate and support cartilage and joint health. When the synovium is attacked, damaged and compromised it can become inflamed, irritated and is no longer able to perform its primary function of maintaining cartilage and joint health.
RA is believed to be a genetic disorder, as scientists have identified a particular genetic marker that increases a patient’s RA risk fivefold.
There are no medicinal cures for arthritis, but the symptoms, such as pain and inflammation, can be managed to make life more comfortable and improve mobility. CBD is believed to help people who struggle with arthritis in two important ways – pain reduction and inflammation reduction.
Chronic pain sufferers of all types have used cannabinoids to help manage pain. Several clinical studies and randomized trials have shown THC and CBD can help reduce pain with less severe side effects or dependency forming issues compared with opioids.
Some of these studies have been performed specifically on CBD’s ability to alleviate osteoarthritis pain. One study examined CBD’s effect on rats with early stages of joint damage. Rats that received local CBD treatments suffered less pain and experienced inflammation reduction. The inflammation reduction allowed the joints to maintain greater stability and actually helped prevent nerve damage from developing in the joints affected by osteoarthritis.
For RA, THC and CBD act as immunosuppressants, essentially reducing and weakening the immune system’s attack on the joint.
CBD also binds to the TRPV1 receptors responsible for sensory perceptions like pain as well as the regulation of body temperature and inflammation. This has the effect of desensitizing the pain receptors and blocking the pain signals being sent to the brain, as well as the inflammatory response.
It should be noted that the majority of studies linking CBD to pain and inflammation reduction were animal studies performed on rats. Many more double-blind human clinical trials need to be performed to gauge CBD’s effects on arthritis-related pain and inflammation for a certainty. However, there are already many osteoarthritis and rheumatoid arthritis sufferers who swear by CBD’s positive effects on their conditions.
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